2766481-17-6

2766481-17-6 structure

2766481-17-6 structure

Name: HPK1-IN-32
Chemical Name: HPK1-IN-32
CAS Number: 2766481-17-6
Molecular Formula: C₂₈H₃₇FN₈O₂
Molecular Weight: 536.64
Catalog: Signaling Pathways MAPK/ERK Pathway MAP4K
Create Date: 2023-04-09 18:47:35
Modify Date: 2024-04-03 13:32:21
HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1].

Name	HPK1-IN-32

Description	HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> MAP4K Research Areas >> Cancer
Target	HPK1
In Vitro	HPK1-IN-32 (Example A34, 0-2 μM, 2 h) 抑制 Jurkat 细胞内 pSLP76 活性，IC50 为 65 nM[1]。
References	[1]. Sanjia XU, et al. 3-[(1h-pyrazol-4-yl)oxy]pyrazin-2-amine compounds as hpk1 inhibitor and use thereof. Patent. WO2022068848.

Molecular Formula	C₂₈H₃₇FN₈O₂
Molecular Weight	536.64