HPK1-IN-25

Names

[ CAS No. ]:
2403600-50-8

[ Name ]:
HPK1-IN-25

Biological Activity

[Description]:

HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAP4K
Research Areas >> Cancer

[Target]

HPK1:129 nM (IC50)


[References]

[1]. Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. WO2019238067A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H25N5O

[ Molecular Weight ]:
387.48

Related Compounds