Thalidomide-O-PEG4-amine

Modify Date: 2025-09-20 12:47:36

Thalidomide-O-PEG4-amine structure	Common Name	Thalidomide-O-PEG4-amine
	CAS Number	2401832-00-4	Molecular Weight	493.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₃₁N₃O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide-O-PEG4-amine

Thalidomide-O-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Thalidomide-O-PEG4-amine

Description	Thalidomide-O-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₃₁N₃O₉
Molecular Weight	493.51
InChIKey	LZFBLPSYUTXWAU-UHFFFAOYSA-N
SMILES	NCCOCCOCCOCCOCCOc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O

Hazard Codes	Xi

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Thalidomide-O-PEG4-amine
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Purity: 98.0%
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