(32-Carbonyl)-RMC-5552
Modify Date: 2025-08-26 18:31:29
(32-Carbonyl)-RMC-5552 structure
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Common Name | (32-Carbonyl)-RMC-5552 | ||
|---|---|---|---|---|
| CAS Number | 2382768-55-8 | Molecular Weight | 1776.11 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C93H134N10O24 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (32-Carbonyl)-RMC-5552(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1]. |
| Name | (32-Carbonyl)-RMC-5552 |
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| Description | (32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C93H134N10O24 |
|---|---|
| Molecular Weight | 1776.11 |
| InChIKey | CHLJLODIXLIFHL-ZDVRXXCFSA-N |
| SMILES | COC1CC2CCC(C)C(O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC(C(C)CC2CCC(OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N3CCc4cc(Cn5nc(-c6ccc7oc(N)nc7c6)c6c(N)ncnc65)ccc4C3)C(OC)C2)CC(=O)C(C)C=C(C)C(O)C(OC)C(=O)C(C)CC(C)C=CC=CC=C1C |