DENV-IN-5

Modify Date: 2024-04-06 18:19:03

DENV-IN-5 structure	Common Name	DENV-IN-5
	CAS Number	2375781-06-7	Molecular Weight	478.99
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₅ClF₂N₄OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DENV-IN-5

DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].

Name	DENV-IN-5

Description	DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Target	HIV (IIIB):0.1512 μM (EC50) DENV-I:1.47 μM (EC50) DENV-II:9.23 μM (EC50) DENV-III:7.08 μM (EC50) DENV-IV:8.91 μM (EC50)
References	[1]. Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.

Molecular Formula	C₂₃H₂₅ClF₂N₄OS
Molecular Weight	478.99

DENV-IN-5

Use of DENV-IN-5

Names

DENV-IN-5 Biological Activity

Chemical & Physical Properties