2375781-06-7

2375781-06-7 structure
2375781-06-7 structure
  • Name: DENV-IN-5
  • Chemical Name: DENV-IN-5
  • CAS Number: 2375781-06-7
  • Molecular Formula: C23H25ClF2N4OS
  • Molecular Weight: 478.99
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2022-09-27 15:22:25
  • Modify Date: 2024-04-06 18:19:03
  • DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].

Name DENV-IN-5
Description DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].
Related Catalog
Target

HIV (IIIB):0.1512 μM (EC50)

DENV-I:1.47 μM (EC50)

DENV-II:9.23 μM (EC50)

DENV-III:7.08 μM (EC50)

DENV-IV:8.91 μM (EC50)

References

[1]. Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.

Molecular Formula C23H25ClF2N4OS
Molecular Weight 478.99