Thalidomide-NH-PEG3-CH2CHO

Modify Date: 2025-09-06 07:23:24

Thalidomide-NH-PEG3-CH2CHO structure	Common Name	Thalidomide-NH-PEG3-CH2CHO
	CAS Number	2360530-43-2	Molecular Weight	447.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₅N₃O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide-NH-PEG3-CH2CHO

Thalidomide-NH-PEG3-CH2CHO is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-PEG3-CH2CHO can be connected to the ligand for protein by a linker to form PROTAC BCL-XL degrader XZ739 (HY-133557)[1].

Name	Thalidomide-NH-PEG3-CH2CHO

Description	Thalidomide-NH-PEG3-CH2CHO is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-NH-PEG3-CH2CHO can be connected to the ligand for protein by a linker to form PROTAC BCL-XL degrader XZ739 (HY-133557)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	Cereblon
References	[1]. Xuan Zhang,et al. Discovery of PROTAC BCL-X L Degraders as Potent Anticancer Agents With Low On-Target Platelet Toxicity. Eur J Med Chem. 2020 Apr 15;192:112186.

Molecular Formula	C₂₁H₂₅N₃O₈
Molecular Weight	447.44

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Thalidomide-NH-PEG3-CH2CHO

Use of Thalidomide-NH-PEG3-CH2CHO

Names

Thalidomide-NH-PEG3-CH2CHO Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.