4-Bromo-2-fluoroanisole

Modify Date: 2024-01-09 17:13:44

4-Bromo-2-fluoroanisole Structure
4-Bromo-2-fluoroanisole structure
Common Name 4-Bromo-2-fluoroanisole
CAS Number 2357-52-0 Molecular Weight 205.024
Density 1.5±0.1 g/cm3 Boiling Point 215.1±20.0 °C at 760 mmHg
Molecular Formula C7H6BrFO Melting Point 16 °C
MSDS Chinese USA Flash Point 98.3±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-bromo-2-fluoro-1-methoxybenzene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 215.1±20.0 °C at 760 mmHg
Melting Point 16 °C
Molecular Formula C7H6BrFO
Molecular Weight 205.024
Flash Point 98.3±0.0 °C
Exact Mass 203.958603
PSA 9.23000
LogP 3.16
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.519
Water Solubility insoluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2909309090

 Synthetic Route

~91%

4-Bromo-2-fluoroanisole Structure

4-Bromo-2-fluor...

CAS#:2357-52-0

Literature: Nippon Mining Co., Ltd. Patent: US5098602 A1, 1992 ;

~%

4-Bromo-2-fluoroanisole Structure

4-Bromo-2-fluor...

CAS#:2357-52-0

Literature: WO2005/123748 A1, ; Page/Page column 85 ; WO 2005/123748 A1

~%

4-Bromo-2-fluoroanisole Structure

4-Bromo-2-fluor...

CAS#:2357-52-0

Literature: Journal of the American Chemical Society, , vol. 81, p. 94,95, 97

~43%

4-Bromo-2-fluoroanisole Structure

4-Bromo-2-fluor...

CAS#:2357-52-0

Literature: Journal of Fluorine Chemistry, , vol. 102, # 1-2 p. 169 - 173

 Customs

HS Code 2909309090
Summary 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles4

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CYP 17 and CYP 19 inhibitors. Evaluation of fluorine effects on the inhibiting activity of regioselectively fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles.

J. Enzyme Inhib. Med. Chem. 19(2) , 145-55, (2004)

Regioselectively fluorinated 1-(naphth-2-ylmethyl)imidazoles 1a-h have been synthesized starting from the corresponding (naphth-2-yl)methanols (2). 2a-d have been obtained by LiAlH4-promoted reduction...

Design of molecular architectures for polymeric mesophase formation. Pugh C, et al.

Macromol. Symp. 98(1) , (1995)

Syntheses of Phenylbicyclohexane Liquid Crystals with Terminal Difluoromethoxy Group [J]. Li J, et al.

Fine Chemicals 12 , 004, (2004)

 Synonyms

3-fluoro-4-methoxybromobenzene
Benzene, 4-bromo-2-fluoro-1-methoxy-
4-Bromo-2-fluorophenyl methyl ether
4-brom-2-fluor-1-methoxybenzol
4-BROMO-2-FLUOROPHENYLMETHYL ETHER
p-bromo-o-fluoroanisole
4-Bromo-2-fluoroanisole
FR CE FO1
Benzene,4-bromo-2-fluoro-1-methoxy
3,4-Difluorobenzoic acid
MFCD00011710
2-fluoro-4-bromo anisole
EINECS 219-096-2
1-Bromo-3-fluoro-4-methoxybenzene
4-Bromo-2-fluoro-1-methoxybenzene
3-fluoro-4-methoxy-1-bromobenzene
1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI)