Ethyl (diethoxyphosphoryl)(fluoro)acetate

Modify Date: 2025-08-21 00:22:53

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure
Ethyl (diethoxyphosphoryl)(fluoro)acetate structure
Common Name Ethyl (diethoxyphosphoryl)(fluoro)acetate
CAS Number 2356-16-3 Molecular Weight 242.182
Density 1.2±0.1 g/cm3 Boiling Point 339.5±0.0 °C at 760 mmHg
Molecular Formula C8H16FO5P Melting Point N/A
MSDS Chinese USA Flash Point 73.9±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name ethyl 2-diethoxyphosphoryl-2-fluoroacetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 339.5±0.0 °C at 760 mmHg
Molecular Formula C8H16FO5P
Molecular Weight 242.182
Flash Point 73.9±0.0 °C
Exact Mass 242.071945
PSA 71.64000
LogP 1.23
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.411

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2931900090

 Synthetic Route

~91%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Kiddle, James J.; Gurley, Alison F. Phosphorus, Sulfur and Silicon and Related Elements, 2000 , vol. 160, p. 195 - 205

~76%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Davis, Franklin A.; Han, Wei; Murphy, Christopher K. Journal of Organic Chemistry, 1995 , vol. 60, # 15 p. 4730 - 4737

~%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: US5180737 A1, ;

~36%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Journal of Fluorine Chemistry, , vol. 92, # 1 p. 45 - 52

~72%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Kvicala, Jaroslav; Vlasakova, Ruzena; Plocar, Jakub; Paleta, Oldrich; Pelter, Andrew Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 5 p. 772 - 788

~%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Synthetic Communications, , vol. 24, # 9 p. 1317 - 1322

~%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Justus Liebigs Annalen der Chemie, , vol. 693, p. 134 - 157

~%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 7, p. 241 - 243 Zhurnal Organicheskoi Khimii, , vol. 7, p. 249 - 251

~%

Ethyl (diethoxyphosphoryl)(fluoro)acetate Structure

Ethyl (diethoxy...

CAS#:2356-16-3

Literature: Tetrahedron, , vol. 53, # 18 p. 6391 - 6400

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Articles1

More Articles
Synthesis and gastrointestinal pharmacology of the 4-fluoro analogue of enisoprost.

J. Med. Chem. 30 , 1952, (1987)

A 4-fluoro analogue of enisoprost was prepared and evaluated for gastric antisecretory and mucosal protective activity in animals. The synthesis centered upon cuprate chemistry but also involved a Wit...

 Synonyms

Diethyl [(ethoxycarbonyl)fluoromethyl]phosphonate
(Diethoxyphosphinyl)fluoroacetic acid,ethyl ester
triethyl phosphonofluoroacetate
ethyl 2-(diethoxyphosphoryl)-2-fluoroacetate
(diethoxy-phosphoryl)-fluoro-acetic acid ethyl ester
Acetic acid, (diethoxyphosphinyl)fluoro-, ethyl ester
Ethyl (Diethoxyphosphinyl)fluoroacetate
Triethyl fluorophosphonoacetate
Triethyl 2-fluoro-2-phosphonoacetate
(EtO)2P(O)CHFCO2Et
Ethyl diethylphosphonofluoroacetate
Ethyl (diethoxyphosphoryl)(fluoro)acetate
2-Fluoro-2-phosphonoacetic Acid Triethyl Ester
MFCD00134400
Acetic acid, 2-(diethoxyphosphinyl)-2-fluoro-, ethyl ester
ethyl 2-(diethoxycarbonyl)-2-fluoroacetate
(Diethoxyphosphinyl)fluoroacetic Acid Ethyl Ester
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