DBCO-PEG4-NH-Boc

Modify Date: 2024-01-10 10:56:15

DBCO-PEG4-NH-Boc Structure
DBCO-PEG4-NH-Boc structure
Common Name DBCO-PEG4-NH-Boc
CAS Number 2353410-17-8 Molecular Weight 623.74
Density N/A Boiling Point N/A
Molecular Formula C34H45N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG4-NH-Boc


DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG4-NH-Boc

 DBCO-PEG4-NH-Boc Biological Activity

Description DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H45N3O8
Molecular Weight 623.74