Ninerafaxstat trihydrochloride

Modify Date: 2024-04-03 13:50:54

Ninerafaxstat trihydrochloride Structure
Ninerafaxstat trihydrochloride structure
Common Name Ninerafaxstat trihydrochloride
CAS Number 2311824-72-1 Molecular Weight 524.87
Density N/A Boiling Point N/A
Molecular Formula C22H32Cl3N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ninerafaxstat trihydrochloride


Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxidation (inhibiting 3-ketoacyl CoA thiolase)[1].

 Names

Name 3-Pyridinecarboxylic acid, 2-[4-[(2,3,4-trimethoxyphenyl)methyl]-1-piperazinyl]ethyl ester, hydrochloride (1:3)

 Ninerafaxstat trihydrochloride Biological Activity

Description Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxidation (inhibiting 3-ketoacyl CoA thiolase)[1].
Related Catalog
References

[1]. Larry Tremaine, et al. Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy. METABOLISM AND PHYSIOLOGY. 8 Nov 2021.

 Chemical & Physical Properties

Molecular Formula C22H32Cl3N3O5
Molecular Weight 524.87
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