Ninerafaxstat trihydrochloride

Names

[ Name ]:
Ninerafaxstat trihydrochloride

Biological Activity

[Description]:

Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxidation (inhibiting 3-ketoacyl CoA thiolase)[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Metabolic Disease

[References]

[1]. Larry Tremaine, et al. Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy. METABOLISM AND PHYSIOLOGY. 8 Nov 2021.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₂Cl₃N₃O₅

[ Molecular Weight ]:
524.87

Related Compounds

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