2311824-72-1

2311824-72-1 structure

Name: Ninerafaxstat trihydrochloride
Chemical Name: 3-Pyridinecarboxylic acid, 2-[4-[(2,3,4-trimethoxyphenyl)methyl]-1-piperazinyl]ethyl ester, hydrochloride (1:3)
CAS Number: 2311824-72-1
Molecular Formula: C₂₂H₃₂Cl₃N₃O₅
Molecular Weight: 524.87
Catalog: Research Areas Cancer
Create Date: 2022-11-22 13:38:25
Modify Date: 2024-04-03 13:50:54
Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxidation (inhibiting 3-ketoacyl CoA thiolase)[1].

Name	3-Pyridinecarboxylic acid, 2-[4-[(2,3,4-trimethoxyphenyl)methyl]-1-piperazinyl]ethyl ester, hydrochloride (1:3)

Description	Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxidation (inhibiting 3-ketoacyl CoA thiolase)[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Metabolic Disease
References	[1]. Larry Tremaine, et al. Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy. METABOLISM AND PHYSIOLOGY. 8 Nov 2021.

Molecular Formula	C₂₂H₃₂Cl₃N₃O₅
Molecular Weight	524.87