IU1-248

Modify Date: 2024-01-10 16:33:26

IU1-248 Structure
IU1-248 structure
Common Name IU1-248
CAS Number 2307472-03-1 Molecular Weight 337.42
Density N/A Boiling Point N/A
Molecular Formula C20H23N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IU1-248


IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.

 Names

Name IU1-248

 IU1-248 Biological Activity

Description IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.
Related Catalog
In Vitro IU1-248 exhibits an IC50 value of 0.83 μM toward USP14, which is comparable to that of IU1-47 (IC50=0.68 μM) and 10-fold more potent than that of IU1 (IC50=12.25 μM)[1].
References

[1]. Yiwei Wang, et al. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res. 2018 Dec;28(12):1186-1194.

 Chemical & Physical Properties

Molecular Formula C20H23N3O2
Molecular Weight 337.42
Storage condition 2-8°C
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

IU1-248 suppliers

IU1-248 price

Related Compounds: More...
IU1
314245-33-5
IU1-47
670270-31-2
sodium 2-[4-[4-[4-[bis(2-cyanoethyl)amino]benzylidene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]phenyl]-6-methylbenzothiazole-7-sulphonate]
27045-88-1
[(3aR,8bS)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-(10-piperidin-1-yldecyl)carbamate
154619-91-7
[N,N,N,N',N',N',N'',N'',N''-nonamethyl-29H,31H-phthalocyaninetrimethylammoniumato(2-)-N29,N30,N31,N32]copper(3+) trichloride
26854-10-4
4-[[2-chloro-4-[3-chloro-4-[[3-methyl-1-(4-methylphenyl)-5-oxo-4H-pyrazol-4-yl]diazenyl]phenyl]phenyl]diazenyl]-5-methyl-2-phenyl-4H-pyrazol-3-one
26841-50-9
Antimycin A2
27220-57-1
C.I.Direct Blue 248
12222-13-8
curium sesquioxide (248)Cm2O3, monoclinic
12371-27-6
2-(2-methoxyphenoxy)-N-[(2E)-4-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2(3H)-ylidene]acetamide
1144477-00-8
2-cyclopentyl-N-[(2E)-4,5-dimethyl-1,3-thiazol-2(3H)-ylidene]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxamide
1144456-40-5
N-(3-aminooxypropyl)pyridine-3-carboxamide
1176426-55-3
N-[(5-Methyl-2-pyrazinyl)carbonyl]-L-phenylalanine
1046118-66-4
2-(4-bromophenoxy)-N-[(2E)-4-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2(3H)-ylidene]acetamide
1144480-30-7
N-[(2E)-4-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2(3H)-ylidene]-5-phenyl-1,2-oxazole-3-carboxamide
1144480-40-9
1-(5-cyclopropyl-1-methyl-1H-pyrazol-3-yl)methanamine
1174305-90-8
N-[2-(3,5-dimethylphenoxy)ethyl]cyclopentanecarboxamide
1172978-31-2
5-(2-Chloro-5-nitrophenyl)-3-(3,4-dichlorophenyl)-1,2,4-oxadiazole
1119395-94-6
1-(4-acetylpiperazin-1-yl)-2-(6-chloro-1H-indol-1-yl)ethanone
1144440-09-4