E3 ligase Ligand 15

Modify Date: 2025-12-09 18:23:42

E3 ligase Ligand 15 Structure
E3 ligase Ligand 15 structure
Common Name E3 ligase Ligand 15
CAS Number 2306390-08-7 Molecular Weight 639.53
Density N/A Boiling Point N/A
Molecular Formula C32H32Cl2N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of E3 ligase Ligand 15


E3 ligase Ligand 15 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 15 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

 Names

Name E3 ligase Ligand 15
Synonym More Synonyms

 E3 ligase Ligand 15 Biological Activity

Description E3 ligase Ligand 15 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 15 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog
References

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

 Chemical & Physical Properties

Molecular Formula C32H32Cl2N4O6
Molecular Weight 639.53
InChIKey CYFZSMNCDNFMOG-IHLOFXLRSA-N
SMILES COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCN(CC(=O)O)C(=O)C2)c(OC(C)C)c1

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD32197284
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