E3 ligase Ligand-Linker Conjugates 36

Modify Date: 2025-08-26 22:37:03

E3 ligase Ligand-Linker Conjugates 36 Structure
E3 ligase Ligand-Linker Conjugates 36 structure
Common Name E3 ligase Ligand-Linker Conjugates 36
CAS Number 1351169-40-8 Molecular Weight 719.82
Density N/A Boiling Point N/A
Molecular Formula C39H49N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of E3 ligase Ligand-Linker Conjugates 36


E3 ligase Ligand-Linker Conjugates 36 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 36 can be used to design PROTAC degrader[1].

 Names

Name E3 ligase Ligand-Linker Conjugates 36

 E3 ligase Ligand-Linker Conjugates 36 Biological Activity

Description E3 ligase Ligand-Linker Conjugates 36 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 36 can be used to design PROTAC degrader[1].
Related Catalog
Target

cIAP1

References

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

 Chemical & Physical Properties

Molecular Formula C39H49N3O10
Molecular Weight 719.82
InChIKey DCRUHCTZKLQUKA-UHFFFAOYSA-N
SMILES CC(C)CC(NC(=O)C(O)C(Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCOCC(=O)O
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