VZ 185

Modify Date: 2025-08-25 19:05:25

VZ 185 structure	Common Name	VZ 185
	CAS Number	2306193-61-1	Molecular Weight	995.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₃H₆₇FN₈O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VZ 185

VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively.

Name	VZ185

Description	VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	DC50: 4.5 nM (BRD7), 1.8 nM (BRD9)[1]
References	[1]. Zoppi V, et al. Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7. J Med Chem. 2019 Jan 24;62(2):699-726.

Molecular Formula	C₅₃H₆₇FN₈O₈S
Molecular Weight	995.21

Hazard Codes	Xi

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: VZ185
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: VZ185
Price: ￥2890.0/100mg
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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