Exatecan intermediate 9

Modify Date: 2025-09-26 03:08:33

Exatecan intermediate 9 structure	Common Name	Exatecan intermediate 9
	CAS Number	2290562-59-1	Molecular Weight	477.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₄FN₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Exatecan intermediate 9

Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].

Name	Exatecan intermediate 9

Description	Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

Molecular Formula	C₂₆H₂₄FN₃O₅
Molecular Weight	477.48
InChIKey	SRCUCWPOTBGIQM-IHZSNKTASA-N
SMILES	CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(F)c(C)c3c1c2C(NC(C)=O)CC3

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Exatecan intermediate 9

Use of Exatecan intermediate 9

Names

Exatecan intermediate 9 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.