2290562-59-1

2290562-59-1 structure

Name: Exatecan intermediate 9
Chemical Name: Exatecan intermediate 9
CAS Number: 2290562-59-1
Molecular Formula: C₂₆H₂₄FN₃O₅
Molecular Weight: 477.48
Catalog: Research Areas Cancer
Create Date: 2024-01-30 08:07:21
Modify Date: 2024-01-30 08:07:21
Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].

Name	Exatecan intermediate 9

Description	Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

Molecular Formula	C₂₆H₂₄FN₃O₅
Molecular Weight	477.48