(E/Z)-E64FC26

Modify Date: 2024-01-05 20:00:26

(E/Z)-E64FC26 Structure
(E/Z)-E64FC26 structure
Common Name (E/Z)-E64FC26
CAS Number 2285446-67-3 Molecular Weight 340.38
Density N/A Boiling Point N/A
Molecular Formula C19H23F3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (E/Z)-E64FC26


(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity[1][2].

 Names

Name (E/Z)-E64FC26

 (E/Z)-E64FC26 Biological Activity

Description (E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity[1][2].
Related Catalog
References

[1]. Nathan G. Dolloff, et al. Indene derivatives and uses thereof. US20190062298A1.

[2]. Robinson RM, et al. Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma. Leukemia. 2019 Apr;33(4):1011-1022.

 Chemical & Physical Properties

Molecular Formula C19H23F3O2
Molecular Weight 340.38
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