(S)-tert-Butyl 2-cyanopyrrolidine-1-carboxylate

Modify Date: 2025-08-26 22:10:38

(S)-tert-Butyl 2-cyanopyrrolidine-1-carboxylate structure	Common Name	(S)-tert-Butyl 2-cyanopyrrolidine-1-carboxylate
	CAS Number	228244-04-0	Molecular Weight	196.246
	Density	1.1±0.1 g/cm3	Boiling Point	307.9±35.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₆N₂O₂	Melting Point	33-36ºC
	MSDS	Chinese	Flash Point	140.0±25.9 °C

Name	tert-butyl (2S)-2-cyanopyrrolidine-1-carboxylate
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	307.9±35.0 °C at 760 mmHg
Melting Point	33-36ºC
Molecular Formula	C₁₀H₁₆N₂O₂
Molecular Weight	196.246
Flash Point	140.0±25.9 °C
Exact Mass	196.121185
PSA	53.33000
LogP	0.40
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.489
Storage condition	0-10°C

MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi
Risk Phrases	R20/21/22
Safety Phrases	26-36/37/39
RIDADR	UN 3439
HS Code	2933990090

Precursor 10
CAS#:35150-07-3 Boc-Pro-NH2 CAS#:15761-39-4 Boc-L-Proline CAS#:79-37-8 Oxalyl chloride CAS#:108-77-0 Cyanuric chloride
CAS#:135097-23-3 1,2-Pyrrolidine... CAS#:24424-99-5 Di-tert-butyl d... CAS#:147-85-3 Proline CAS#:7531-52-4 L-Prolinamide
CAS#:37784-17-1 Boc-D-Pro-OH CAS#:344-25-2 H-D-Pro-OH
DownStream 3
CAS#:274901-16-5 Vildagliptin (L... CAS#:207557-35-5 (2S)-1-(Chloroa... CAS#:119020-01-8 (S)-1-Boc-2-(am...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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J. Med. Chem. 46 , 4543, (2003)

Isophthalic acid bis(l-prolyl-pyrrolidine) amide is a very potent prolyl oligopeptidase inhibitor, but it has a log P value of -0.2, which is very low for a compound targeted to the brain. Therefore, ...

Constrained peptidomimetics reveal detailed geometric requirements of covalent prolyl oligopeptidase inhibitors.

J. Med. Chem. 52 , 6672-84, (2009)

Prolyl oligopeptidases cleave peptides on the carboxy side of internal proline residues and their inhibition has potential in the treatment of human brain disorders. Using our docking program fitted, ...

2-Methyl-2-propanyl (2S)-2-cyano-1-pyrrolidinecarboxylate

(s)-1-n-boc-2-cyanopyrrolidine

S-(-)-1-Boc-2-pyrrolidinecarbonitrile

MFCD01861225

N-tert-butyloxycarbonyl proline nitrile

(S)-tert-Butyl 2-cyanopyrrolidine-1-carboxylate