(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

Modify Date: 2024-01-02 15:06:56

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure
(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile structure
Common Name (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
CAS Number 207557-35-5 Molecular Weight 172.612
Density 1.3±0.1 g/cm3 Boiling Point 363.1±37.0 °C at 760 mmHg
Molecular Formula C7H9ClN2O Melting Point 64 °C
MSDS N/A Flash Point 173.4±26.5 °C

 Names

Name (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 363.1±37.0 °C at 760 mmHg
Melting Point 64 °C
Molecular Formula C7H9ClN2O
Molecular Weight 172.612
Flash Point 173.4±26.5 °C
Exact Mass 172.040344
PSA 44.10000
LogP -0.62
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.519

 Safety Information

HS Code 2942000000

 Synthetic Route

~66%

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: Medichem, S.A. Patent: US2008/167479 A1, 2008 ; Location in patent: Page/Page column 5 ;

~88%

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: Peng, Jun; Feng, Yue; Tao, Zhu; Chen, Yingjie; Hu, Xiangnan Letters in Organic Chemistry, 2013 , vol. 10, # 3 p. 159 - 163

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(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: ALEMBIC PHARMACEUTICALS LIMITED; JAYARAMAN, Venkat Raman; PILLAI, Bijukumar Gopinathan; KEVAT, Jitendra; DUBADIA, Bhagwati; KAUSHAL, Anupriya Patent: WO2014/20462 A1, 2014 ; Location in patent: Page/Page column 9 ;

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(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: Journal of Medicinal Chemistry, , vol. 46, # 13 p. 2774 - 2789

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(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: WO2006/90244 A1, ; Page/Page column 28 ; WO 2006/090244 A1

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(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: WO2011/101861 A1, ;

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(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: Letters in Organic Chemistry, , vol. 10, # 3 p. 159 - 163

~%

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: WO2014/20462 A1, ;

~%

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Structure

(2S)-1-(Chloroa...

CAS#:207557-35-5

Literature: WO2014/20462 A1, ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
1-chloroacetyl-2-(S)-pyrrolidinecarbonitrile
1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2S)-
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
(2S)-1-(chloroacetyl)-2-cyanopyrrolidine
(2S)1-(CHLOROACETYL)-2-PYRROLIDINE CARBONITRILE
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