3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID

Modify Date: 2023-01-16 19:18:56

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID Structure
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID structure
Common Name 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID
CAS Number 227619-64-9 Molecular Weight 172.14
Density N/A Boiling Point N/A
Molecular Formula C6H8N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID


(±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].

 Names

Name (±)-HIP-A,(±)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylicacid
Synonym More Synonyms

  Biological Activity

Description (±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].
Related Catalog
References

[1]. Andrea Pinto, et al. Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters.

 Chemical & Physical Properties

Molecular Formula C6H8N2O4
Molecular Weight 172.14
Exact Mass 172.04800
PSA 91.15000

 Synonyms

hip-a
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