Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID
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Purity: 98.0%
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227619-64-9

227619-64-9 structure

Name: 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-4-CARBOXYLIC ACID
Chemical Name: (±)-HIP-A,(±)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylicacid
CAS Number: 227619-64-9
Molecular Formula: C₆H₈N₂O₄
Molecular Weight: 172.14
Catalog: Signaling Pathways Membrane Transporter/Ion Channel EAAT2
Create Date: 2016-03-11 13:49:13
Modify Date: 2023-01-16 19:18:56
(±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].

Name	(±)-HIP-A,(±)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylicacid
Synonyms	hip-a

Description	(±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> EAAT2 Research Areas >> Neurological Disease
References	[1]. Andrea Pinto, et al. Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters.