RWJ-445167
Modify Date: 2024-01-10 12:08:46
RWJ-445167 structure
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Common Name | RWJ-445167 | ||
|---|---|---|---|---|
| CAS Number | 226566-43-4 | Molecular Weight | 436.485 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H24N6O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RWJ-445167RWJ-445167 is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. |
| Name | RWJ-445167 |
|---|---|
| Synonym | More Synonyms |
| Description | RWJ-445167 is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. |
|---|---|
| Related Catalog | |
| Target |
Ki: 4.0 nM (thrombin), 230 nM (factor Xa)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C18H24N6O5S |
| Molecular Weight | 436.485 |
| Exact Mass | 436.152893 |
| LogP | -0.17 |
| Index of Refraction | 1.644 |
| InChIKey | GHCPCZIUEYRYJT-UHFFFAOYSA-N |
| SMILES | Cc1cccc(S(=O)(=O)Nc2ccc(C)n(CC(=O)NCCON=C(N)N)c2=O)c1 |
| Storage condition | 2-8℃ |
| N-[2-(Carbamimidamidooxy)ethyl]-2-[6-methyl-3-{[(3-methylphenyl)sulfonyl]amino}-2-oxo-1(2H)-pyridinyl]acetamide |
| 1(2H)-Pyridineacetamide, N-[2-[[(aminoiminomethyl)amino]oxy]ethyl]-6-methyl-3-[[(3-methylphenyl)sulfonyl]amino]-2-oxo- |
| N-[2-(carbamimidamidooxy)ethyl]-2-[6-methyl-3-{[(3-methylphenyl)sulfonyl]amino}-2-oxopyridin-1(2H)-yl]acetamide |