RWJ 50271
Modify Date: 2025-08-26 22:20:41
RWJ 50271 structure
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Common Name | RWJ 50271 | ||
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| CAS Number | 162112-37-0 | Molecular Weight | 410.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H17F3N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RWJ 50271RWJ 50271 is an selective inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells)[1]. |
| Name | N-(3-Hydroxypropyl)-5-methyl-1-{4-[3-(trifluoromethyl)phenyl]-1,3 -thiazol-2-yl}-1H-pyrazole-4-carboxamide |
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| Description | RWJ 50271 is an selective inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells)[1]. |
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| Related Catalog | |
| Target |
IC50: 5.0 μM (LFA-1/ICAM-1, HL60 cells)[1] |
| References |
| Molecular Formula | C18H17F3N4O2S |
|---|---|
| Molecular Weight | 410.41 |
| Exact Mass | 410.10200 |
| PSA | 111.77000 |
| LogP | 4.01000 |
| InChIKey | HOFGTYCLOKDAES-UHFFFAOYSA-N |
| SMILES | Cc1c(C(=O)NCCCO)cnn1-c1nc(-c2cccc(C(F)(F)F)c2)cs1 |