Antibacterial agent 115

Modify Date: 2024-01-17 23:31:30

Antibacterial agent 115 Structure
Antibacterial agent 115 structure
Common Name Antibacterial agent 115
CAS Number 2259732-60-8 Molecular Weight 544.77
Density N/A Boiling Point N/A
Molecular Formula C35H48N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antibacterial agent 115


Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent[1].

 Names

Name Antibacterial agent 115

 Antibacterial agent 115 Biological Activity

Description Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent[1].
Related Catalog
In Vitro Antibacterial agent 115 (Compound 10) shows antibacterial activity with MIC values of both 2.72 μg/mL against Staphylococcus aureussubsp.aureus (ATCC 29213), Staphylococcus epidermidis (ATCC 12228) and Staphylococcus aureus (ATCC 6538)[1].
In Vivo Antibacterial agent 115 (Compound 10) (0-40 mg/kg; i.g.; seven consecutive days) shows anti-inflammatory activity[1]. Animal Model: Kunming female mice (body weight 18–22 g), 12-O-tetradecylphorbol-13- acetate (TPA) induced ear edema mice model[1]. Dosage: 10, 20, 40 mg/kg Administration: Gavage, seven consecutive days Result: Inhibited swelling of mouse ears and inhibited the expression of TNF-α, IL-1β and p65.
References

[1]. Yang Y, et al. Synthesis, anti-microbial and anti-inflammatory activities of 18β-glycyrrhetinic acid derivatives. Bioorg Chem. 2020 Aug;101:103985.

 Chemical & Physical Properties

Molecular Formula C35H48N2O3
Molecular Weight 544.77
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