HTT-D3
Modify Date: 2025-09-09 10:17:38
HTT-D3 structure
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Common Name | HTT-D3 | ||
|---|---|---|---|---|
| CAS Number | 2254502-89-9 | Molecular Weight | 404.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H25FN6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HTT-D3HTT-D3 is a potent and orally active huntingtin (HTT) splicing modulator. HTT-D3 acts by promoting the inclusion of a pseudoexon containing a premature termination codon (stop-codon psiExon), leading to HTT mRNA degradation and reduction of HTT levels. HTT-D3 reduces p-glycoprotein (P-gp) efflux, and can be uesd for Huntington's disease research[1]. |
| Name | HTT-D3 |
|---|
| Description | HTT-D3 is a potent and orally active huntingtin (HTT) splicing modulator. HTT-D3 acts by promoting the inclusion of a pseudoexon containing a premature termination codon (stop-codon psiExon), leading to HTT mRNA degradation and reduction of HTT levels. HTT-D3 reduces p-glycoprotein (P-gp) efflux, and can be uesd for Huntington's disease research[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C23H25FN6 |
|---|---|
| Molecular Weight | 404.48 |
| InChIKey | APXTULSKNLWAOS-UHFFFAOYSA-N |
| SMILES | CCN1CCC(c2cc3c(F)cc(-c4cc(C)c5nc(C)cn5n4)cc3nn2)CC1 |