JWG-071

Modify Date: 2024-01-15 11:45:24

JWG-071 structure	Common Name	JWG-071
	CAS Number	2250323-50-1	Molecular Weight	612.76
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₄₄N₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JWG-071

JWG-071 is the first reported kinase-selective chemical probe for ERK5. JWG-071 improves ERK5 activity and BRD4 selectivity. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology[1].

Name	JWG-071

Description	JWG-071 is the first reported kinase-selective chemical probe for ERK5. JWG-071 improves ERK5 activity and BRD4 selectivity. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
Target	ERK5:88 nM (IC50)
In Vitro	JWG-071 inhibits ERK5 and LRRK2 with IC50 of 88 and 109 nM, respectively[1].
References	[1]. Wang J, et al. Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinonesas Inhibitors of Kinases and Bromodomains. ACS Chem Biol. 2018 Sep 21;13(9):2438-2448

Molecular Formula	C₃₄H₄₄N₈O₃
Molecular Weight	612.76

DC Chemicals Limited
China
Product Name: JWG-071
Price: $350.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

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Price: ￥1900/1 mg

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JWG-071

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