GPR84 antagonist 2

Modify Date: 2024-01-11 23:38:52

GPR84 antagonist 2 structure	Common Name	GPR84 antagonist 2
	CAS Number	2244269-74-5	Molecular Weight	605.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₁₆Cl₂NaO₄PS₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GPR84 antagonist 2

GPR84 antagonist 2 (compound 33) is a potent, selective, and orally active GPR84 antagonist (IC50=8.95 nM). GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis[1].

Name	GPR84 antagonist 2

Description	GPR84 antagonist 2 (compound 33) is a potent, selective, and orally active GPR84 antagonist (IC50=8.95 nM). GPR84 antagonist 2 shows improved potency in the calcium mobilization assay and the ability to inhibit the chemotaxis of neutrophils and macrophages upon GPR84 activation. GPR84 antagonist 2 has the potential for the research of ulcerative colitis[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> GPR84
References	[1]. Chen LH, et al. Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis. J Med Chem. 2022;65(5):3991-4006.

Molecular Formula	C₂₈H₁₆Cl₂NaO₄PS₂
Molecular Weight	605.42

DC Chemicals Limited
China
Product Name: GPR84 antagonist 2
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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