Pegsebrenatide

Modify Date: 2024-03-18 20:01:43

Pegsebrenatide Structure
Pegsebrenatide structure
Common Name Pegsebrenatide
CAS Number 2243292-26-2 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C206H318N54O69S2(C2H4O)m+2n; m≈10; n≈20 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pegsebrenatide


Pegsebrenatide (NLY01) is a long-acting GLP-1R agonist. Pegsebrenatide has an extended half-life and favorable blood-brain barrier penetration. Pegsebrenatide can block A1 astrocyte transformation, reducing dopaminergic cell death, and improving motor symptoms in mouse models of PD[1].

 Names

Name Pegsebrenatide

 Pegsebrenatide Biological Activity

Description Pegsebrenatide (NLY01) is a long-acting GLP-1R agonist. Pegsebrenatide has an extended half-life and favorable blood-brain barrier penetration. Pegsebrenatide can block A1 astrocyte transformation, reducing dopaminergic cell death, and improving motor symptoms in mouse models of PD[1].
Related Catalog
References

[1]. Jacob K Sterling, et al.GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension. Cell Rep. 2020, 33, 5.  

 Chemical & Physical Properties

Molecular Formula C206H318N54O69S2(C2H4O)m+2n; m≈10; n≈20
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