2243292-26-2

2243292-26-2 structure

Name: Pegsebrenatide
Chemical Name: Pegsebrenatide
CAS Number: 2243292-26-2
Molecular Formula: C₂₀₆H₃₁₈N₅₄O₆₉S₂(C₂H₄O)m+₂n; m≈₁₀; n≈₂₀
Molecular Weight:
Catalog: Research Areas Neurological Disease
Create Date: 2024-03-18 20:01:43
Modify Date: 2024-03-18 20:01:43
Pegsebrenatide (NLY01) is a long-acting GLP-1R agonist. Pegsebrenatide has an extended half-life and favorable blood-brain barrier penetration. Pegsebrenatide can block A1 astrocyte transformation, reducing dopaminergic cell death, and improving motor symptoms in mouse models of PD[1].

Name	Pegsebrenatide

Description	Pegsebrenatide (NLY01) is a long-acting GLP-1R agonist. Pegsebrenatide has an extended half-life and favorable blood-brain barrier penetration. Pegsebrenatide can block A1 astrocyte transformation, reducing dopaminergic cell death, and improving motor symptoms in mouse models of PD[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Jacob K Sterling, et al.GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension. Cell Rep. 2020, 33, 5.

Molecular Formula	C₂₀₆H₃₁₈N₅₄O₆₉S₂(C₂H₄O)m+₂n; m≈₁₀; n≈₂₀