ASP2453

Modify Date: 2024-01-05 17:58:30

ASP2453 structure	Common Name	ASP2453
	CAS Number	2241719-73-1	Molecular Weight	747.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₀H₄₈F₃N₇O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ASP2453

ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.

Name	ASP2453

Description	ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Ras
Target	KRas G12C:40 nM (IC50)
References	[1]. Nakayama A, et al. Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models. Br J Cancer. 2021 Nov 18.

Molecular Formula	C₄₀H₄₈F₃N₇O₄
Molecular Weight	747.85

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ASP2453
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ASP2453
Price: $1500.0/10mg
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

ASP2453 suppliers

ASP2453 price

ASP2453

Use of ASP2453

Names

ASP2453 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.