FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

Modify Date: 2025-08-20 23:17:29

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 Structure
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 structure
Common Name FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
CAS Number 2241669-84-9 Molecular Weight 622.71
Density N/A Boiling Point N/A
Molecular Formula C27H39FN8O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2


FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].

 Names

Name FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

  Biological Activity

Description FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
Related Catalog
References

[1]. Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.

 Chemical & Physical Properties

Molecular Formula C27H39FN8O6S
Molecular Weight 622.71
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