FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

Modify Date: 2024-01-21 13:52:07

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 structure	Common Name	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
	CAS Number	2241669-84-9	Molecular Weight	622.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₉FN₈O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].

Name	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

Description	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.

Molecular Formula	C₂₇H₃₉FN₈O₆S
Molecular Weight	622.71

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

Use of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

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Biological Activity

Chemical & Physical Properties