2241669-84-9

2241669-84-9 structure

Name: FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
Chemical Name: FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
CAS Number: 2241669-84-9
Molecular Formula: C₂₇H₃₉FN₈O₆S
Molecular Weight: 622.71
Catalog: Research Areas Cancer
Create Date: 2022-08-16 18:34:58
Modify Date: 2024-01-21 13:52:07
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].

Name	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

Description	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.

Molecular Formula	C₂₇H₃₉FN₈O₆S
Molecular Weight	622.71