KDM4-IN-4

Modify Date: 2025-10-04 20:00:19

KDM4-IN-4 Structure
KDM4-IN-4 structure
Common Name KDM4-IN-4
CAS Number 2230475-63-3 Molecular Weight 245.36
Density N/A Boiling Point N/A
Molecular Formula C16H23NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KDM4-IN-4


KDM4-IN-4 (compound 47) is a potent histone lysine demethylase 4 (KDM4) inhibitor with a modest affinity binding to ~80 μM for KDM4A-Tudor domain. KDM4-IN-4 can inhibit H3K4Me3 binding to the Tudor domain in cells with an EC50 value of 105 μM. KDM4-IN-4 can be used for researching anticancer[1].

 Names

Name KDM4-IN-4

 KDM4-IN-4 Biological Activity

Description KDM4-IN-4 (compound 47) is a potent histone lysine demethylase 4 (KDM4) inhibitor with a modest affinity binding to ~80 μM for KDM4A-Tudor domain. KDM4-IN-4 can inhibit H3K4Me3 binding to the Tudor domain in cells with an EC50 value of 105 μM. KDM4-IN-4 can be used for researching anticancer[1].
Related Catalog
Target

KDM4A-Tudor domain:80 μM (Ki)

References

[1]. Wu Q, Young B, Wang Y, Davidoff AM, Rankovic Z, Yang J. Recent Advances with KDM4 Inhibitors and Potential Applications. J Med Chem. 2022 Jul 15.

 Chemical & Physical Properties

Molecular Formula C16H23NO
Molecular Weight 245.36
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

KDM4-IN-4 suppliers

KDM4-IN-4 price