KY19382

Modify Date: 2025-08-31 09:43:47

KY19382 Structure
KY19382 structure
Common Name KY19382
CAS Number 2226664-93-1 Molecular Weight 360.19
Density N/A Boiling Point N/A
Molecular Formula C17H11Cl2N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KY19382


KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.

 Names

Name KY19382

 KY19382 Biological Activity

Description KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.

 Chemical & Physical Properties

Molecular Formula C17H11Cl2N3O2
Molecular Weight 360.19
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