2226664-93-1
2226664-93-1 structure
- Name: KY19382
- Chemical Name: KY19382
- CAS Number: 2226664-93-1
- Molecular Formula: C17H11Cl2N3O2
- Molecular Weight: 360.19
- Create Date: 2021-01-08 12:14:46
- Modify Date: 2025-08-31 09:43:47
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KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
| Name | KY19382 |
|---|
| Description | KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases. |
|---|
| Molecular Formula | C17H11Cl2N3O2 |
|---|---|
| Molecular Weight | 360.19 |