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KY19382

Names

[ CAS No. ]:
2226664-93-1

[ Name ]:
KY19382

Biological Activity

[Description]:

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H11Cl2N3O2

[ Molecular Weight ]:
360.19


Related Compounds

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