methyl 6-hydroxyangolensate

Modify Date: 2025-08-23 11:35:31

methyl 6-hydroxyangolensate Structure
methyl 6-hydroxyangolensate structure
Common Name methyl 6-hydroxyangolensate
CAS Number 22255-07-8 Molecular Weight 486.55
Density 1.3±0.1 g/cm3 Boiling Point 630.0±55.0 °C at 760 mmHg
Molecular Formula C27H34O8 Melting Point N/A
MSDS N/A Flash Point 334.8±31.5 °C

 Use of methyl 6-hydroxyangolensate


6-Methylhydroxyyangolensate is a limonoid can be extracted from Khaya grandifoliola. 6-Methylhydroxyyangolensate has low antimalarial activity in vitro, with an IC50 of 21.59 μg/ml against P. falciparum (W2/Indochina clone)[1].

 Names

Name Methyl (2S)-[(1S,3S,7R,8R,9R,12S,13R)-13-(3-furyl)-6,6,8,12-tetramethyl-17-methylene-5,15-dioxo-2,14-dioxatetracyclo[7.7.1.01,12.03,8]heptadec-7-yl](hydroxy)acetate
Synonym More Synonyms

 methyl 6-hydroxyangolensate Biological Activity

Description 6-Methylhydroxyyangolensate is a limonoid can be extracted from Khaya grandifoliola. 6-Methylhydroxyyangolensate has low antimalarial activity in vitro, with an IC50 of 21.59 μg/ml against P. falciparum (W2/Indochina clone)[1].
Related Catalog
References

[1]. Bickii J, et al. In vitro antimalarial activity of limonoids from Khaya grandifoliola C.D.C. (Meliaceae). J Ethnopharmacol. 2000 Jan;69(1):27-33.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 630.0±55.0 °C at 760 mmHg
Molecular Formula C27H34O8
Molecular Weight 486.55
Flash Point 334.8±31.5 °C
Exact Mass 486.225372
PSA 112.27000
LogP 2.23
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.571

 Safety Information

Hazard Codes Xi

 Synonyms

7,12a-Methano-2H,4H-pyrano[4,3-b][1]benzoxocin-8-acetic acid, 4-(3-furanyl)undecahydro-α-hydroxy-4a,7a,9,9-tetramethyl-13-methylene-2,10-dioxo-, methyl ester, (αS,4S,4aS,7R,7aR,8R,11aS,12aS)-
Methyl (2S)-[(1S,3S,7R,8R,9R,12S,13S)-13-(3-furyl)-6,6,8,12-tetramethyl-17-methylene-5,15-dioxo-2,14-dioxatetracyclo[7.7.1.0.0]heptadec-7-yl](hydroxy)acetate
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