Dynarrestin

Modify Date: 2025-08-26 11:17:13

Dynarrestin Structure
Dynarrestin structure
 Common Name Dynarrestin
CAS Number 2222768-84-3 Molecular Weight 431.50
Density N/A Boiling Point N/A
Molecular Formula C22H23F2N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dynarrestin


Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells[1].

 Names

Name Dynarrestin
Synonym More Synonyms

 Dynarrestin Biological Activity

Description Dynarrestin is a aminothiazole inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin rapidly and reversibly inhibits dynein 1-driven microtubule gliding in vitro plus a range of dynein 1- and 2-dependent processes in cells without affecting ATP hydrolysis and interfering with ciliogenesis. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells[1].
Related Catalog
References

[1]. Höing S, et al. Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein. Cell Chem Biol. 2018 Apr 19;25(4):357-369.e6.

 Chemical & Physical Properties

Molecular Formula C22H23F2N3O2S
Molecular Weight 431.50
InChIKey UZNNDDDSGCMQOQ-UHFFFAOYSA-N
SMILES CCOC(=O)c1sc(Nc2ccc(F)cc2F)nc1-c1ccc(N(CC)CC)cc1

 Synonyms

MFCD32174341
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Chemsrc provides Dynarrestin(CAS#:2222768-84-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Dynarrestin are included as well.>> amp version: Dynarrestin

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