(D-Phe11,His12)-Sauvagine (11-40) structure
|
Common Name | (D-Phe11,His12)-Sauvagine (11-40) | ||
|---|---|---|---|---|
| CAS Number | 220673-95-0 | Molecular Weight | 3651.24000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C161H274N48O46S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of (D-Phe11,His12)-Sauvagine (11-40)Antisauvagine-30 (aSvg-30) is a potent, competitive and selective CRF2 receptor antagonist with Kd values of 1.4 nM and 153.6 nM for mouse CRF2β and rat CRF1 receptors, respectively[1]. |
| Name | Antisauvagine-30 |
|---|---|
| Synonym | More Synonyms |
| Description | Antisauvagine-30 (aSvg-30) is a potent, competitive and selective CRF2 receptor antagonist with Kd values of 1.4 nM and 153.6 nM for mouse CRF2β and rat CRF1 receptors, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
Kd: 1.4 nM (mouse CRF2β) ;Kd: 153.6 nM (rat CRF1)[1] |
| References |
| Molecular Formula | C161H274N48O46S |
|---|---|
| Molecular Weight | 3651.24000 |
| Exact Mass | 3649.01000 |
| PSA | 1611.26000 |
| LogP | 8.45320 |
| InChIKey | JDWSXVUWDQFRCE-JBNJRNGTSA-N |
| SMILES | CCC(C)C(NC(=O)C(NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(NC(=O)C(CCC(=O)O)NC(=O)C(NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(N)Cc1ccccc1)C(C)CC)C(C)CC)C(C)O)C(=O)O |
| Safety Phrases | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| H-D-Phe-His-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2 |
| D-PHE-HIS-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THR-ILE-NH2 |
| H-D-PHE-HIS-LEU-LEU-ARG-LYS-MET-ILE-GLU-ILE-GLU-LYS-GLN-GLU-LYS-GLU-LYS-GLN-GLN-ALA-ALA-ASN-ASN-ARG-LEU-LEU-LEU-ASP-THE-ILE-OH |
| M.W. 3650.29 C161H274N48O46S |
| Antisauvagine 30 |