DI-404
Modify Date: 2025-08-25 13:11:22
DI-404 structure
|
Common Name | DI-404 | ||
|---|---|---|---|---|
| CAS Number | 2187412-79-7 | Molecular Weight | 713.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H45ClN6O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DI-404DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members. |
| Name | DI-404 |
|---|
| Description | DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members. |
|---|---|
| References | 1. ZHou HB, Zhou W, Zhou B, Liu L, Chern TR, Chinnaswamy K, Lu J, Bernard D, Yang C, Li S, Wang M, Stuckey JA, Sun Y, Wang S. High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J Med Chem. 2018 Feb 13. doi: 10.1021/acs.jmedchem.7b01455. [Epub ahead of print] PubMed PMID: 29438612. |
| Molecular Formula | C35H45ClN6O6S |
|---|---|
| Molecular Weight | 713.29 |