Methyltetrazine-PEG8-acid

Modify Date: 2025-08-30 18:34:42

Methyltetrazine-PEG8-acid Structure
Methyltetrazine-PEG8-acid structure
Common Name Methyltetrazine-PEG8-acid
CAS Number 2183440-33-5 Molecular Weight 612.67
Density N/A Boiling Point N/A
Molecular Formula C28H44N4O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyltetrazine-PEG8-acid


Methyltetrazine-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methyltetrazine-PEG8-acid

 Methyltetrazine-PEG8-acid Biological Activity

Description Methyltetrazine-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C28H44N4O11
Molecular Weight 612.67
InChIKey JDJSAIBRQJQXLA-UHFFFAOYSA-N
SMILES Cc1nnc(-c2ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)cc2)nn1
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