ROS tracer precursor

Modify Date: 2025-09-22 20:45:07

ROS tracer precursor structure	Common Name	ROS tracer precursor
	CAS Number	2153480-20-5	Molecular Weight	715.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₉H₄₅N₃O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ROS tracer precursor

ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis[1].

Name	ROS tracer precursor

Description	ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vivo	[18F]ROStrace is a radiotracer for imaging superoxide in vivo with positron emission tomography (PET), in an LPS model of neuroinflammation. [18F]ROStrace is found to rapidly cross the blood-brain barrier (BBB) and is trapped in the brain of LPS-treated animals. [18F]ox-ROStrace, the oxidized form of [18F]ROStrace, does not cross the BBB. [18F]ROStrace is a suitable radiotracer for imaging superoxide levels in the central nervous system with PET[1].
References	[1]. Hou C, et al. Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586.

Molecular Formula	C₃₉H₄₅N₃O₈S
Molecular Weight	715.85
InChIKey	PVAWZLJBKPGCNK-UHFFFAOYSA-N
SMILES	Cc1ccc(S(=O)(=O)OCCOc2ccc(C3c4cc(NC(=O)OC(C)(C)C)ccc4-c4ccc(NC(=O)OC(C)(C)C)cc4N3C)cc2)cc1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ROS tracer precursor
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