ROS tracer precursor

Modify Date: 2024-01-13 01:53:37

ROS tracer precursor Structure
ROS tracer precursor structure
Common Name ROS tracer precursor
CAS Number 2153480-20-5 Molecular Weight 715.85
Density N/A Boiling Point N/A
Molecular Formula C39H45N3O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ROS tracer precursor


ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis[1].

 Names

Name ROS tracer precursor

 ROS tracer precursor Biological Activity

Description ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis[1].
Related Catalog
In Vivo [18F]ROStrace is a radiotracer for imaging superoxide in vivo with positron emission tomography (PET), in an LPS model of neuroinflammation. [18F]ROStrace is found to rapidly cross the blood-brain barrier (BBB) and is trapped in the brain of LPS-treated animals. [18F]ox-ROStrace, the oxidized form of [18F]ROStrace, does not cross the BBB. [18F]ROStrace is a suitable radiotracer for imaging superoxide levels in the central nervous system with PET[1].
References

[1]. Hou C, et al. Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586.

 Chemical & Physical Properties

Molecular Formula C39H45N3O8S
Molecular Weight 715.85