Biotin-PEG6-Thalidomide

Modify Date: 2025-08-29 18:12:48

Biotin-PEG6-Thalidomide Structure
Biotin-PEG6-Thalidomide structure
Common Name Biotin-PEG6-Thalidomide
CAS Number 2144775-48-2 Molecular Weight 791.91
Density N/A Boiling Point N/A
Molecular Formula C37H53N5O12S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG6-Thalidomide


Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG6-Thalidomide
Synonym More Synonyms

 Biotin-PEG6-Thalidomide Biological Activity

Description Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C37H53N5O12S
Molecular Weight 791.91

 Synonyms

MFCD31561114
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