1085938-09-5

1085938-09-5 structure

1085938-09-5 structure

Name: Biotin-PEG6-azide
Chemical Name: Biotin-PEG6-azide
CAS Number: 1085938-09-5
Molecular Formula: C₂₄H₄₄N₆O₈S
Molecular Weight: 576.71
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 18:01:28
Modify Date: 2024-01-11 06:56:59
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-PEG6-azide

Description	Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula	C₂₄H₄₄N₆O₈S
Molecular Weight	576.71