1808990-66-0
1808990-66-0 structure
- Name: Biotin-PEG6-Maleimide
- Chemical Name: Biotin-PEG6-Mal
- CAS Number: 1808990-66-0
- Molecular Formula: C31H51N5O11S
- Molecular Weight: 701.828
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-09 00:11:45
- Modify Date: 2024-04-05 22:49:55
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Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Biotin-PEG6-Mal |
|---|---|
| Synonyms |
N-[24-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-22-oxo-3,6,9,12,15,18-hexaoxa-21-azatetracos-1-yl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[24-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-22-oxo-3,6,9,12,15,18-hexaoxa-21-azatetracos-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- MFCD28015769 |
| Description | Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 944.7±65.0 °C at 760 mmHg |
| Molecular Formula | C31H51N5O11S |
| Molecular Weight | 701.828 |
| Flash Point | 525.1±34.3 °C |
| Exact Mass | 701.330566 |
| LogP | -3.19 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.528 |
| Storage condition | -20°C |