Thalidomide-NH-PEG4-Ms
Modify Date: 2025-10-07 14:46:07
Thalidomide-NH-PEG4-Ms structure
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Common Name | Thalidomide-NH-PEG4-Ms | ||
|---|---|---|---|---|
| CAS Number | 2140807-24-3 | Molecular Weight | 527.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H29N3O10S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-PEG4-MsThalidomide-NH-PEG4-Ms is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739[1]. |
| Name | Thalidomide-NH-PEG4-Ms |
|---|
| Description | Thalidomide-NH-PEG4-Ms is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | XZ739, a CRBN-dependent PROTAC BCL-XL degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis[1]. |
| References |
| Molecular Formula | C22H29N3O10S |
|---|---|
| Molecular Weight | 527.54 |
| Hazard Codes | Xi |
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